MHC stands for Major Histocompatibility Complex. These proteins sit on the surface of every cell in your body and act as display platforms — they grab protein fragments from inside the cell and present them to your immune system.
When a cell becomes cancerous, it produces mutated proteins. Your MHC molecules display fragments of these mutated proteins on the cell surface. If your immune system's T cells recognize these fragments as foreign, they attack the cancer cell. Personalized cancer vaccines work by training your T cells to recognize specific cancer fragments — but which fragments work depends entirely on your specific MHC profile.
Your MHC profile is inherited and unique to you. A cancer vaccine designed for one person's MHC may be completely invisible to another person's immune system. That's why MHC typing is essential before designing any personalized treatment.
Your MHC type is encoded in your germline DNA and never changes. ReadyGenome extracts and stores it alongside your genome so that if you ever need personalized treatment, this critical information is immediately available — no additional testing, no delays.
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