In 2024, Sydney tech entrepreneur Paul Conyngham learned that his rescue dog Rosie — an eight-year-old Staffordshire bull terrier cross — had aggressive mast cell cancer. After surgery and chemotherapy failed to stop the tumors from returning, vets told him she had months to live.
Conyngham isn't a doctor or a biologist. He's a data scientist and engineer. Instead of accepting Rosie's prognosis, he did what he knew best — he started asking AI for help. Using ChatGPT and Grok, he researched cancer immunotherapy and identified a possible path: a personalized mRNA vaccine designed specifically for Rosie's tumors.
Conyngham paid researchers at the University of New South Wales to sequence both Rosie's healthy DNA and her tumor DNA. This comparison revealed the specific mutations driving her cancer — the delta between healthy and sick. This is exactly why having a baseline genome stored in advance matters so profoundly.
Using AlphaFold for protein structure prediction and AI tools for neoantigen identification, Conyngham identified which mutated proteins would be visible to Rosie's immune system. UNSW's RNA Institute then designed and manufactured a custom mRNA vaccine in less than two months. After vaccination, most of Rosie's tumors shrank significantly, and she went back to chasing rabbits.
The exact same process — genome sequencing, tumor comparison, neoantigen identification, MHC binding prediction, and mRNA vaccine design — applies to human cancer treatment. The key difference is regulatory: human trials require extensive approvals that veterinary treatments don't. But the science is identical, and clinical trials are already underway at BioNTech, Moderna, and Memorial Sloan Kettering.
The single biggest bottleneck in Rosie's treatment was getting the baseline genome sequenced. If Rosie's genome had already been stored, the entire process would have started weeks earlier. ReadyGenome exists so that when this technology is available for your family — human or pet — you won't be waiting for sequencing. You'll be ready.
Related: What Paul Got Right About Cancer Treatment · mRNA Cancer Vaccines in 2026 · View Pricing
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